Aliant IntimACTIV is a delicate intimate detergent that can be used frequently generally without causing skin irritation. It contains plant extracts well known for their eudermic and antinflammatory properties, such as Aloe Vera and Calendula. It also contains Glyceryl monolaurate, Tea Tree Oil and Octenidine that harbour antimicrobial activity.
Aliant IntimACTIV contains Glyceryl monolaurate, Octenidine, Glycyrrhetic acid, Tea Tree Oil, Vitamin B5, Calendula and Aloe Vera.
Glyceryl Monolaurate is a natural compound with antimycotic and antimicrobial activity. As an example it can impair the growth of Candida Albicans and modulate the host inflammatory reactions. Octenidine is an antiseptic compound. Glycyrrhetinic acid is derived from licorice and can reduce oxidative damage in tissues and interfere with the synthesis of inflammatory cytokines. Tea Tree Oil is extracted from Malaleuca Alternifolia. Due to its content of highly lipophilic terpenes, Tea Tree oil can damage bacterial cell membranes, leading to leakage of ions and nucleic acids. It can also interfere with LPS-induced proinflammatory cytokines and prostaglandins synthesis. Furthermore it is able to alter the cellular and mitochondrial membrane permeability of fungi. Vitamin B5 has moisturizing and eudermic properties and can favour skin healing and regeneration processes. Calendula has lenitive and rebalancing action. Aloe Vera is well known for its hydrating, antinflammatory and healing properties. It can indeed stimulate growth and activity of macrophages and fibroblasts and dampen the synthesis of proinflammatory molecules.
Pour a small amount of Aliant IntimACTIV on the hand or a wash cloth and cleanse gently. Rinse thoroughly. The detergent can be diluted with water.
Cosmetic for external use.
Strandberg KL, Peterson ML, Lin YC, Pack MC, Chase DJ, Schlievert PM., Glycerol monolaurate inhibits Candida and Gardnerella vaginalis in vitro and in vivo but not Lactobacillus. Antimicrob Agents Chemother. 2010 Feb;54(2):597-601.;
Carson CF, Hammer KA, Riley TV., Melaleuca alternifolia (Tea Tree) oil: a review of antimicrobial and other medicinal properties. Clin Microbiol Rev. 2006 Jan;19(1):50-62. Review. ;
Camargo FB Jr, Gaspar LR, Maia Campos PM., Skin moisturizing effects of panthenol-based formulations. J Cosmet Sci. 2011 Jul-Aug;62(4):361-70. ;
Panahi Y, Davoudi SM, Sahebkar A, Beiraghdar F, Dadjo Y, Feizi I, Amirchoopani G, Zamani A., Efficacy of Aloe vera/olive oil cream versus betamethasone cream for chronic skin lesions following sulfur mustard exposure: a randomized double-blind clinical trial. Cutan Ocul Toxicol. 2012 Jun;31(2):95-103. ;
Löffler H, Happle R., Profile of irritant patch testing with detergents: sodium lauryl sulfate, sodium laureth sulfate and alkyl polyglucoside. Contact Dermatitis. 2003 Jan;48(1):26-32.;
Savić S, Tamburić S, Savić MM., From conventional towards new – natural surfactants in drug delivery systems design: current status and perspectives. Expert Opin Drug Deliv. 2010 Mar;7(3):353-69. ;
Akhtar N, Zaman SU, Khan BA, Amir MN, Ebrahimzadeh MA., Calendula extract: effects on mechanical parameters of human skin. Acta Pol Pharm. 2011 Sep-Oct;68(5):693-701. ;
Park HY, Park SH, Yoon HK, Han MJ, Kim DH., Anti-allergic activity of 18beta-glycyrrhetinic acid-3-O-beta-D-glucuronide. Arch Pharm Res. 2004 Jan;27(1):57-60.;
Araújo LU, Grabe-Guimarães A, Mosqueira VC, Carneiro CM, Silva-Barcellos NM., Profile of wound healing process induced by allantoin. Acta Cir Bras. 2010 Oct;25(5):460-6.;
Pazyar N, Yaghoobi R, Bagherani N, Kazerouni A., A review of applications of tea tree oil in dermatology. Int J Dermatol. 2012 Sep 24.;
Mimoz O., Chlorhexidine is better than aqueous povidone iodine as skin antiseptic for preventing surgical site infections. Infect Control Hosp Epidemiol. 2012 Sep;33(9):961-2.;
Chapman AK, Aucott SW, Milstone AM., Safety of chlorhexidine gluconate used for skin antisepsis in the preterm infant. J Perinatol. 2012 Jan;32(1):4-9.